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Journal of Korean Neurosurgical Society 1988;17(6): 1309-1316.
Measurement and Imaging of Regional Cerebral Blood Flow(rCBF) with Xenon-Enhanced CT(XECT).
Young Shin Ra, Tae Sub Chung, Seung Kon Huh, Jung Ho Suh, Kyu Chang Lee
1Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.
2Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
ABSTRACT
A non-invasive technique for measuring regional cerebral blood flow by xenon-enhanced CT has been developed with advent of computed tomography and reported extensively in recent years. Inhaled non-radioactive xenon gas can make tissue contrast enhancement on CT scan. Attenuation change from time dependent xenon concentration in brain CT slice are used to derive both parition coefficient and rCBF. In spite of its limited slice, it appears to be a useful and potentially widely available technique for clinical examination of rCBF in cerebrovascular disease, and it provides blood flow information with relatively high degree of spatial resolution and anatomical correlation. In this report, we present four clinical cases of various conditions and discuss methodology.
Key Words: Cerebral blood flow; Xenon; Computed tomography; Cerebrovascular disease
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